A SURROGATE MEASURE FOR PATIENT REPORTED SYMPTOM REMISSION IN ADMINISTRATIVE DATA

Abstract Background In real-world pragmatic administrative databases, patient reported remission is often missing.Objective We evaluate if, in administrative data, five features of antidepressant use patterns can replace patient-reported symptom remission.Method We re-examined data from Sequence Treatment Alternatives to Relieve Depression (STAR*D)

Leaf senescence, the last stage of leaf development, is a well-regulated and complex process for investigation.For simplification, dark-induced leaf senescence has frequently been used to mimic the natural senescence of leaves because many typical senescence symptoms, such as chlorophyll (Chl) and protein degradation, also occur under darkness.In t